Description

n-(4-Methoxyphenyl)-5-Methoxyspiro[Cyclohexane-1,3'-Indoline]-2'-Carboxamide is a high-purity, complex organic compound featuring a unique spirocyclic indoline structure. This compound is valued for its role as a sophisticated chemical intermediate in advanced pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and life science industries for synthesizing novel active ingredients and exploring new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its complex heterocyclic core.
• Organic Synthesis: Serves as a versatile precursor for constructing complex spirocyclic and indoline-based frameworks in academic and industrial laboratories.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Material Science Research: Investigated as a potential monomer or additive for specialty polymers with specific optical or electronic properties.

Basic Information

Product Name	n-(4-Methoxyphenyl)-5-Methoxyspiro[Cyclohexane-1,3'-Indoline]-2'-Carboxamide
CAS No.	18392-02-4
Molecular Formula	C22H24N2O3
Molecular Weight	364.44 g/mol
Synonyms	5-Methoxy-N-(4-methoxyphenyl)spiro[cyclohexane-1,3'-indoline]-2'-carboxamide; Spiro[cyclohexane-1,3'-indole]-2'-carboxamide, 5-methoxy-N-(4-methoxyphenyl)-; 18392-02-4; 5-Methoxy-N-(p-methoxyphenyl)spiro[cyclohexane-1,3'-indoline]-2'-carboxamide; n-(4-Methoxyphenyl)-5-methoxyspiro[cyclohexane-1,3'-indoline]-2'-carboxamide
EINECS	Contact for details

Quality Control

Our n-(4-Methoxyphenyl)-5-Methoxyspiro[Cyclohexane-1,3'-Indoline]-2'-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.