Description

Methyl 2,3-Difluorobenzoate is a versatile fluorinated aromatic ester, a key building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the aromatic ring, which significantly influences the electronic and steric properties of downstream molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate for developing active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorobenzene moiety to modulate potency and pharmacokinetics.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved biological activity and environmental profile.
• Liquid Crystal Materials: Serves as a starting material for fluorinated compounds used in electronic displays, leveraging fluorine's properties to affect dielectric anisotropy and viscosity.
• Organic Electronics: Employed in the synthesis of fluorinated organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Advanced Polymer Chemistry: Acts as a monomer or modifier for introducing fluorine into polymer backbones, enhancing chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: A valuable reagent in medicinal chemistry and material science R&D for structure-activity relationship (SAR) studies and novel compound library generation.

Basic Information

Product Name	Methyl 2,3-Difluorobenzoate
CAS No.	18355-74-3
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	2,3-Difluorobenzoic Acid Methyl Ester; Methyl 2,3-Difluorobenzoate; Benzoic acid, 2,3-difluoro-, methyl ester; 2,3-Difluorobenzoic acid methyl ester; Methyl o,m-difluorobenzoate; Methyl 2,3-difluorobenzenecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2,3-Difluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.