Description

Spiro[3.4]Oct-1-Ene-2-Carboxamide (8Ci) is a specialized spirocyclic organic compound featuring a unique fused ring structure that serves as a valuable synthetic intermediate. This compound matters for its role in facilitating complex molecular construction, particularly in the development of novel pharmacophores and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for use in medicinal chemistry programs and as a building block for high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring complex spirocyclic or bridged ring systems for target engagement.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore new chemical space and improve the pharmacokinetic properties of therapeutic molecules.
• Agrochemical Synthesis: Serves as a precursor in the development of new active ingredients for crop protection with potential novel modes of action.
• Material Science: Investigated as a monomer or precursor for creating polymers with unique thermal or mechanical properties due to its strained ring system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Catalyst Ligand Development: The carboxamide and olefin functionalities can be modified to create novel ligands for asymmetric catalysis.

Basic Information

Product Name	Spiro[3.4]Oct-1-Ene-2-Carboxamide (8Ci)
CAS No.	18316-70-6
Molecular Formula	C9H13NO
Molecular Weight	151.21 g/mol
Synonyms	Spiro[3.4]oct-1-ene-2-carboxamide; 1-Azaspiro[4.4]non-1-ene-2-carboxamide; 2-Carbamoylspiro[3.4]oct-1-ene; 8CI Spiro Compound; Spirocyclic Carboxamide Intermediate; Bridged Bicyclic Carboxamide
EINECS	Contact for details

Quality Control

Our Spiro[3.4]Oct-1-Ene-2-Carboxamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ISO 9001 standards underpin our reliable supply chain for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.