Description

(Trimethylsilyl)Methyl Thiocyanate is a versatile organosilicon reagent featuring both a silyl-protecting group and a reactive thiocyanate moiety. This compound matters for its utility as a key synthetic intermediate in the preparation of functionalized organosilanes and heterocyclic compounds, enabling advanced material and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those requiring silicon-containing bioactive molecules or thiocyanate-derived functional groups.
• Agrochemical Synthesis: Serves as a building block for creating new pesticides and herbicides with enhanced properties.
• Material Science Research: Employed in the development of advanced polymers, coatings, and silicon-based hybrid materials.
• Organic Synthesis Reagent: Acts as a source of the -SCN group for nucleophilic substitution reactions or as a precursor to other sulfur-containing functionalities.
• Cross-coupling Reactions: Utilized in palladium-catalyzed reactions to introduce the (trimethylsilyl)methyl moiety into complex molecules.
• Ligand and Catalyst Development: Provides a scaffold for constructing novel ligands used in asymmetric catalysis.

Basic Information

Product Name	(Trimethylsilyl)Methyl Thiocyanate
CAS No.	18293-51-1
Molecular Formula	C5H11NSSi
Molecular Weight	145.31 g/mol
Synonyms	((Trimethylsilyl)methyl) thiocyanate; (Trimethylsilylmethyl) thiocyanate; Thiocyanic acid, (trimethylsilyl)methyl ester; NSC 168087; (Trimethylsilyl)methanethiocyanate; TMS-methyl thiocyanate; Trimethylsilylmethyl isothiocyanate (common misnomer); (CH3)3SiCH2SCN
EINECS	Contact for details

Quality Control

Our (Trimethylsilyl)Methyl Thiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.