Description

[S,(+)]-1-O,2-o-Distearoyl-3-o-Trityl-L-Glycerol is a high-purity, enantiomerically pure synthetic intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a protected glycerol derivative, enabling the stereoselective construction of complex lipids and phospholipids. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel drug delivery systems, lipid-based therapeutics, and specialized surfactants.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of phospholipids, prodrugs, and other bioactive lipid molecules.
• Lipid Research: Used in academic and industrial research to study membrane biophysics, lipid metabolism, and enzyme kinetics.
• Drug Delivery Systems: Serves as a precursor for creating specialized lipid components in liposomes, nanoparticles, and other advanced carrier technologies.
• Asymmetric Synthesis: Utilized in stereocontrolled chemical reactions due to its defined (S)-configuration at the glycerol backbone.
• Bioconjugation Chemistry: The trityl-protected hydroxyl group provides a handle for selective deprotection and further functionalization.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in lipid analysis.

Basic Information

Product Name	[S,(+)]-1-O,2-o-Distearoyl-3-o-Trityl-L-Glycerol
CAS No.	18289-92-4
Molecular Formula	C72H112O5
Molecular Weight	1057.66 g/mol
Synonyms	(S)-1,2-Distearoyl-3-trityl-sn-glycerol; 1,2-Di-O-stearoyl-3-O-trityl-sn-glycerol; sn-Glycerol 1,2-distearate 3-trityl ether; L-α-Distearoyl-β-tritylglycerol; 3-O-Trityl-1,2-di-O-stearoyl-sn-glycerol; Trityl-protected DAG; 1,2-Distearoyl-3-tritylglycerol; (S)-(+)-1,2-Distearoyl-3-tritylglycerol
EINECS	Contact for details

Quality Control

Our [S,(+)]-1-O,2-o-Distearoyl-3-o-Trityl-L-Glycerol is manufactured under strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and enantiomeric excess meet the stringent requirements for research and pharmaceutical applications. Comprehensive analytical data, including HPLC, NMR, and optical rotation, are documented. A Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is stable under inert atmosphere. Keep away from strong alkali and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.