Description

3-Pyridineacrylonitrile, α-(m-Chlorophenyl)-β-Hydroxy- (8Ci) is a specialized organic intermediate featuring a pyridine core substituted with a nitrile and a chlorophenyl-hydroxyl moiety. This compound matters for its role as a versatile building block in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by research chemists and process development teams for creating novel active ingredients, including potential kinase inhibitors and other biologically relevant heterocycles.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting specific enzymes or receptors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis: Serves as a versatile building block for creating more complex pyridine and acrylonitrile derivatives in organic chemistry.
• Material Science Research: Potential monomer or additive in the development of specialty polymers and advanced functional materials.
• Academic & Contract Research: Valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	3-Pyridineacrylonitrile, α-(m-Chlorophenyl)-β-Hydroxy- (8Ci)
CAS No.	18206-80-9
Molecular Formula	C14H11ClN2O
Molecular Weight	258.70 g/mol
Synonyms	α-(3-Chlorophenyl)-β-hydroxy-3-pyridineacrylonitrile; 3-[2-(3-Chlorophenyl)-2-hydroxyethenyl]pyridine-1-carbonitrile; (E/Z)-2-(3-Chlorophenyl)-3-(pyridin-3-yl)acrylonitrile hydrate; 3-Pyridineacrylonitrile, α-(3-chlorophenyl)-β-hydroxy-; NSC 339586; (m-Chlorophenyl)(3-pyridyl)hydroxyacrylonitrile; 3-(2-(3-Chlorophenyl)-2-hydroxyvinyl)pyridine-1-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Pyridineacrylonitrile, α-(m-Chlorophenyl)-β-Hydroxy- (8Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We are committed to meeting the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.