Description

Spiro[3.5]Nona-1,6-Diene-2-Carboxamide (7Ci,8Ci) is a specialized spirocyclic organic compound with the CAS registry number 18205-68-0, serving as a valuable synthetic intermediate in advanced organic chemistry. Its unique fused ring structure and reactive diene/carboxamide functionalities make it a critical building block for constructing complex molecular architectures. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients and functional molecules.

Application

This spirocyclic diene carboxamide is a versatile synthon with applications across several high-tech chemical industries:

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets, leveraging its constrained three-dimensional geometry.
• Agrochemical Research: Used in developing new generations of herbicides and insecticides, where the spiro structure can impart favorable biological activity and environmental profiles.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions and other cycloadditions to create complex polycyclic compounds for academic and industrial research.
• Ligand and Catalyst Development: Utilized in the design of novel chiral ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	Spiro[3.5]Nona-1,6-Diene-2-Carboxamide (7Ci,8Ci)
CAS No.	18205-68-0
Molecular Formula	C10H13NO
Molecular Weight	163.22 g/mol
Synonyms	7-Cyano-8-azaspiro[4.5]deca-1,6-diene; Spiro[3.5]nona-1,6-diene-2-carboxamide; 2-Carbamoylspiro[3.5]nona-1,6-diene; 18205-68-0; 7-Cyano-8-azaspirodeca-1,6-diene; Spiro(3.5)nona-1,6-diene-2-carboxamide
EINECS	Contact for details

Quality Control

Our Spiro[3.5]Nona-1,6-Diene-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.