Description

3-Bromopropionic Acid Trimethylsilyl Ester is a versatile organosilicon reagent used as a key building block in organic synthesis. This compound is valued for its ability to introduce the 3-bromopropionyl moiety under mild conditions, serving as a protected form of 3-bromopropionic acid. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of active pharmaceutical ingredients (APIs), complex molecules, and functionalized polymers.

Application

• Pharmaceutical Intermediate: A crucial synthon for constructing drug candidates, particularly in nucleoside and protease inhibitor synthesis.
• Agrochemical Synthesis: Used in the production of herbicides and plant growth regulators requiring the 3-bromopropionate functional group.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Peptide Chemistry: Employed for the side-chain modification of peptides and the synthesis of peptide mimetics.
• Ligand and Catalyst Preparation: Useful for synthesizing phosphine and other chelating ligands used in homogeneous catalysis.
• Material Science Research: Applied in surface functionalization and the development of novel silicon-containing hybrid materials.

Basic Information

Product Name	3-Bromopropionic Acid Trimethylsilyl Ester
CAS No.	18187-28-5
Molecular Formula	C6H13BrO2Si
Molecular Weight	225.16 g/mol
Synonyms	Trimethylsilyl 3-Bromopropionate; 3-Bromopropionic Acid TMS Ester; (3-Bromopropanoyloxy)trimethylsilane; Propanoic acid, 3-bromo-, trimethylsilyl ester; TMS 3-Bromopropionate; Trimethylsilyl 3-Bromopropanoate; 3-Bromopropanoyl Trimethylsilyl Ester; Silane, (3-bromopropanoyloxy)trimethyl-
EINECS	Contact for details

Quality Control

Our 3-Bromopropionic Acid Trimethylsilyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, NMR, and HPLC to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.