Description

Methyl 4-Iodosalicylate is a halogenated aromatic ester of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block, particularly for introducing the 4-iodosalicylate moiety into complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates. Its defined structure and reactivity make it a critical reagent for cross-coupling reactions and structure-activity relationship studies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting inflammation or metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: An essential substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Sonogashira couplings to form biaryl and other complex structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.

Basic Information

Item	Detail
Product Name	Methyl 4-Iodosalicylate
CAS No.	18179-39-0
Molecular Formula	C8H7IO3
Molecular Weight	278.05 g/mol
Synonyms	Methyl 4-Iodosalicylate; Methyl 2-Hydroxy-4-iodobenzoate; 4-Iodosalicylic Acid Methyl Ester; 2-Hydroxy-4-iodobenzoic Acid Methyl Ester; Benzoic acid, 2-hydroxy-4-iodo-, methyl ester; Methyl 4-iodo-2-hydroxybenzoate; 4-Iodo-2-hydroxybenzoic acid methyl ester; Methyl 4-iodosalicylate
EINECS	Contact for details

Quality Control

Our Methyl 4-Iodosalicylate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, IR for identification, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.