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1-(2-Trimethylsilylethyl)Piperidine CAS NO 18132-66-6


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CAS No.:18132-66-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(2-Trimethylsilylethyl)Piperidine is a specialized organosilicon compound featuring a piperidine ring linked to a trimethylsilylethyl group, making it a valuable building block in advanced organic synthesis. This compound is particularly significant for its role as a protected amine intermediate and a versatile synthon in the development of complex molecules. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Serves as a key protected amine precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
  • Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the silyl group can act as a temporary protecting group or influence bioavailability.
  • Ligand and Catalyst Development: Employed as a building block for creating novel nitrogen-containing ligands used in asymmetric catalysis and transition metal complexes.
  • Material Science Research: Functions as a monomer or modifier in the synthesis of specialty polymers, silicones, and advanced organic-inorganic hybrid materials.
  • Organic Synthesis Reagent: Acts as a versatile nucleophile or a base in various organic transformations, including alkylation and acylation reactions.
  • Chemical Research & Development: Utilized in academic and industrial R&D labs for methodological studies and the exploration of new synthetic pathways.

Basic Information

Product Name 1-(2-Trimethylsilylethyl)Piperidine
CAS No. 18132-66-6
Molecular Formula C10H23NSi
Molecular Weight 185.38 g/mol
Synonyms 1-[(2-Trimethylsilyl)ethyl]piperidine; 2-(1-Piperidinyl)ethyltrimethylsilane; 2-(Piperidin-1-yl)ethyltrimethylsilane; N-(2-Trimethylsilylethyl)piperidine; 1-(2-Trimethylsilylethyl)piperidine; 1-(2-Trimethylsilylethyl)piperidine; (2-Piperidinoethyl)trimethylsilane; Trimethyl[2-(1-piperidinyl)ethyl]silane
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Quality Control

Our 1-(2-Trimethylsilylethyl)Piperidine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms
Purity (GC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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