Description

5-Methanesulfonyl-1H-Pyridin-2-One is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its unique sulfonyl-substituted pyridinone structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides with novel modes of action.
• Material Science Research: Serves as a precursor for developing specialty polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	5-Methanesulfonyl-1H-Pyridin-2-One
CAS No.	18085-51-3
Molecular Formula	C6H7NO3S
Molecular Weight	173.19 g/mol
Synonyms	5-(Methylsulfonyl)-2(1H)-pyridinone; 5-Methylsulfonyl-2-pyridone; 2-Hydroxy-5-(methylsulfonyl)pyridine; 1H-Pyridin-2-one, 5-(methylsulfonyl)-; 5-Methanesulfonyl-2(1H)-pyridone; 5-Methanesulfonylpyridin-2-ol; 18085-51-3
EINECS	Contact for details

Quality Control

Our 5-Methanesulfonyl-1H-Pyridin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, IR for identification, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.