Description

Nonanedioic Acid Bis(Trimethylsilyl) Ester is a high-purity, volatile silylating agent derived from azelaic acid. This compound is valued for its role as a key derivatization reagent in analytical chemistry, enhancing the volatility and thermal stability of target analytes for precise detection. It is primarily utilized by analytical laboratories and R&D chemists in the pharmaceutical, agrochemical, and material science sectors for gas chromatography (GC) and mass spectrometry (MS) applications.

Application

• Analytical Derivatization for GC/MS: Used to silylate carboxylic acids, alcohols, and other polar functional groups to improve their chromatographic performance and detection sensitivity.
• Pharmaceutical Impurity Profiling: Employed in the analysis of drug metabolites and related substances to facilitate accurate identification and quantification.
• Polymer and Material Science Research: Serves as a monomer or modifying agent in the synthesis of specialized silicon-containing polymers and coatings.
• Agrochemical Analysis: Applied in the derivatization of pesticides, herbicides, and their degradation products for environmental and residue testing.
• Metabolomics and Proteomics: A critical reagent for preparing samples in complex biological studies to enable comprehensive profiling of small molecules.
• Organic Synthesis Intermediate: Acts as a protected form of azelaic acid or as a trimethylsilyl donor in multi-step synthetic routes.

Basic Information

Product Name	Nonanedioic Acid Bis(Trimethylsilyl) Ester
CAS No.	17906-08-0
Molecular Formula	C15H34O4Si2
Molecular Weight	334.61 g/mol
Synonyms	Azelaic Acid Bis(trimethylsilyl) Ester; Bis(trimethylsilyl) Azelate; 1,9-Bis(trimethylsilyloxy)-1,9-dioxononane; Nonanedioic Acid Bis-O-(trimethylsilyl) Ester; TMS Azelate; Azelaic Acid TMS Ester; Trimethylsilyl Azelate; Azelaic Acid, Bis(trimethylsilyl) Ester
EINECS	Contact for details

Quality Control

Our Nonanedioic Acid Bis(Trimethylsilyl) Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive analytical applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the rigorous standards of analytical and research laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.