Description

4-Oxo-6,7,8,9-Tetrahydro-4H-Quinolizine-1-Carboxylic Acid Methyl Ester is a high-purity, versatile heterocyclic building block and key synthetic intermediate. This compound is valued for its rigid fused-ring structure, which is integral to constructing complex molecular architectures in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and fine chemical manufacturers for applications in medicinal chemistry, including the synthesis of novel active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel quinolizidine and related alkaloid analogs for drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold for developing new chemical entities with potential biological activity.
• Agrochemical Synthesis: Serves as a key intermediate in the production of advanced crop protection agents and pesticides.
• Fine Chemical Production: Employed in the manufacture of complex specialty chemicals, dyes, and functional materials.
• Academic & R&D: Utilized in university and institutional laboratories for methodological studies and heterocyclic chemistry research.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for custom synthesis projects.

Basic Information

Product Name	4-Oxo-6,7,8,9-Tetrahydro-4H-Quinolizine-1-Carboxylic Acid Methyl Ester
CAS No.	17891-06-4
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	Methyl 4-oxo-6,7,8,9-tetrahydro-4H-quinolizine-1-carboxylate; 1-Carbomethoxy-4-oxo-6,7,8,9-tetrahydro-4H-quinolizine; 4H-Quinolizine-1-carboxylic acid, 4-oxo-6,7,8,9-tetrahydro-, methyl ester; Methyl 4-oxo-4H-quinolizine-1-carboxylate (tetrahydro); Quinolizine methyl ester derivative
EINECS	Contact for details

Quality Control

Our 4-Oxo-6,7,8,9-Tetrahydro-4H-Quinolizine-1-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.