Description

2-[(Trimethylsilyl)Oxy]Phenol is a versatile organosilicon compound featuring a phenol group protected by a trimethylsilyl (TMS) ether. This chemical serves as a crucial protected intermediate in organic synthesis, offering enhanced stability and solubility for sensitive reactions. It is primarily utilized by research chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly where phenol protection is required.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and other crop protection agents.
• Polymer & Material Science: Acts as a monomer or functionalization agent in the production of specialty silicones and high-performance polymers.
• Organic Synthesis Reagent: Employed as a protected phenol synthon in multi-step laboratory and pilot-scale syntheses.
• Liquid Crystal & Electronic Chemicals: Utilized in the manufacture of advanced materials for display and semiconductor applications.
• Flavor & Fragrance Industry: Intermediate for the synthesis of complex aromatic compounds.

Basic Information

Product Name	2-[(Trimethylsilyl)Oxy]Phenol
CAS No.	17881-86-6
Molecular Formula	C9H14O2Si
Molecular Weight	182.29 g/mol
Synonyms	2-(Trimethylsiloxy)phenol; o-(Trimethylsiloxy)phenol; Phenol, 2-[(trimethylsilyl)oxy]-; 2-Hydroxyphenyl trimethylsilyl ether; TMS-protected catechol; 2-TMS-oxy phenol; 1-Hydroxy-2-(trimethylsiloxy)benzene; 17881-86-6
EINECS	Contact for details

Quality Control

Our 2-[(Trimethylsilyl)Oxy]Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep container tightly sealed when not in use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.