Description

2-Trimethylsilylmethylpyridine is a versatile organosilicon reagent featuring a reactive pyridine ring and a trimethylsilylmethyl group. This compound is valued for its role as a key building block in organic synthesis, particularly in the development of pharmaceuticals and advanced materials. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce silyl-protected functionalities or create novel heterocyclic systems.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Ligand and Catalyst Preparation: Acts as a starting material for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of silicon-containing polymers and advanced organic electronic materials.
• Organic Synthesis Reagent: Functions as a protected synthon or a coupling partner in cross-coupling reactions and nucleophilic substitutions.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry in exploring new synthetic pathways.

Basic Information

Product Name	2-Trimethylsilylmethylpyridine
CAS No.	17881-80-0
Molecular Formula	C9H15NSi
Molecular Weight	165.31 g/mol
Synonyms	2-((Trimethylsilyl)methyl)pyridine; Pyridine, 2-[(trimethylsilyl)methyl]-; 2-Pyridylmethyltrimethylsilane; (2-Pyridylmethyl)trimethylsilane; Trimethyl(2-pyridylmethyl)silane; 2-TMSM-Pyridine; 2-(Trimethylsilylmethyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Trimethylsilylmethylpyridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.