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(4-Bromophenoxy)Trimethylsilane CAS NO 17878-44-3


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CAS No.:17878-44-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(4-Bromophenoxy)Trimethylsilane is a versatile organosilicon reagent featuring a bromophenoxy functional group. This compound is valued for its role as a key synthetic intermediate and protecting group in advanced organic synthesis, particularly in the construction of complex molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require high-purity building blocks for coupling reactions and functional group manipulation.

Application

  • Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
  • Agrochemical Synthesis: Serves as a key building block for creating advanced herbicides, fungicides, and plant growth regulators.
  • Liquid Crystal & OLED Material Precursor: Employed in the production of organic electronic materials and liquid crystal displays (LCDs) due to its stable silane and aromatic bromine moieties.
  • Polymer & Resin Modification: Acts as a functional monomer or cross-linking agent to introduce specific properties into silicone-based polymers and advanced resins.
  • Organic Synthesis Reagent: Functions as a protecting group for phenols or as a versatile electrophile in nucleophilic substitution reactions in laboratory-scale and process chemistry.
  • Chemical Research & Development: A valuable tool for medicinal chemists and material scientists exploring new molecular entities and functional materials.

Basic Information

Item Detail
Product Name (4-Bromophenoxy)Trimethylsilane
CAS No. 17878-44-3
Molecular Formula C9H13BrOSi
Molecular Weight 245.19 g/mol
Synonyms 1-Bromo-4-(trimethylsilyloxy)benzene; 4-Bromophenyl trimethylsilyl ether; p-Bromophenoxytrimethylsilane; Trimethyl(4-bromophenoxy)silane; (p-Bromophenoxy)trimethylsilane; 4-Bromophenol trimethylsilyl ether; O-Trimethylsilyl-4-bromophenol; TMS-4-bromophenol ether
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Quality Control

Our (4-Bromophenoxy)Trimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (GC/HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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