Description

2,4,5,6-Tetrachloro-Nicotinonitrile is a halogenated pyridine derivative, specifically a tetrachlorinated nicotinonitrile, serving as a versatile and high-value synthetic intermediate. Its unique structure makes it a critical building block for the development of advanced agrochemicals and active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing chemists in the fine chemical, pharmaceutical, and agrochemical industries seeking to introduce complex halogenated motifs into their target molecules.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, where the chlorinated pyridine core contributes to biological activity.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as non-linear optical (NLO) materials and charge-transport layers, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and proprietary intermediates under cGMP conditions where required.

Basic Information

Product Name	2,4,5,6-Tetrachloro-Nicotinonitrile
CAS No.	17824-82-7
Molecular Formula	C6HCl4N2
Molecular Weight	247.89 g/mol
Synonyms	2,4,5,6-Tetrachloropyridine-3-carbonitrile; 3-Cyano-2,4,5,6-tetrachloropyridine; Tetrachloronicotinonitrile; Nicotinonitrile, 2,4,5,6-tetrachloro-; 2,4,5,6-Tetrachloro-3-cyanopyridine
EINECS	Contact for details

Quality Control

Our 2,4,5,6-Tetrachloro-Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets precise customer specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We adhere to relevant ISO and cGMP guidelines for the production of fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.