Description

1-Naphthyl Phosphate Calcium Salt Trihydrate is an organophosphate salt widely utilized as a key biochemical reagent and synthetic intermediate. Its primary commercial value lies in its role as a substrate for alkaline phosphatase enzymes in diagnostic and research applications, enabling critical detection and quantification processes. This compound is essential for manufacturers and research institutions in the life sciences, pharmaceutical development, and clinical diagnostics sectors.

Application

• Enzyme Substrate in Diagnostics: Used as a chromogenic or fluorogenic substrate for alkaline phosphatase (ALP) in ELISA, immunohistochemistry (IHC), and Western blotting.
• Biochemical Research: Employed in enzymatic assays to study phosphatase activity, enzyme kinetics, and inhibition studies.
• Pharmaceutical Intermediates: Serves as a building block in the synthesis of more complex pharmaceutical compounds and prodrugs.
• Clinical Chemistry Reagents: A component in formulated kits for the clinical measurement of ALP levels, an important biomarker for liver and bone disorders.
• Life Science Reagents: Supplied to manufacturers of high-purity reagents and buffers for molecular biology and cell culture applications.
• Industrial Catalysis: Potential use as a ligand or precursor in catalytic systems for organic synthesis.

Basic Information

Product Name	1-Naphthyl Phosphate Calcium Salt Trihydrate
CAS No.	17805-69-5
Molecular Formula	C10H9CaO4P · 3H2O
Molecular Weight	326.25 g/mol (Anhydrous basis)
Synonyms	Calcium 1-Naphthyl Phosphate Trihydrate; 1-Naphthyl Phosphate Calcium Salt; α-Naphthyl Phosphate Calcium Salt; Phosphoric Acid 1-Naphthyl Ester Calcium Salt Trihydrate; ALP Substrate; NSC 401008; 1-Naphthyl Dihydrogen Phosphate Calcium Salt; α-Naphthylphosphate Calcium Salt
EINECS	Contact for details

Quality Control

Our 1-Naphthyl Phosphate Calcium Salt Trihydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and residual solvent analysis, to ensure it meets stringent specifications for research and diagnostic use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	12.0 - 16.0% (Theoretical for Trihydrate: ~16.5%)
Heavy Metals (as Pb)	≤ 20 ppm
Solubility	Soluble in water, slightly soluble in ethanol
pH (1% Solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.