Description

(3R,4R)-3,4-Dihydroxyoxolan-2-One CAS NO 17675-99-9 is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and functional group array make it a critical precursor for the development of complex, biologically active molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Asymmetric Catalysis Research: Serves as a starting material or ligand precursor in the development of new stereoselective catalytic processes.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural products, specialty chemicals, and advanced materials.
• Biochemical Research: Employed in studies involving carbohydrate chemistry and as a model compound for enzymatic transformations.
• Agrochemical Development: Potential intermediate in the synthesis of novel, chiral crop protection agents with enhanced specificity.

Basic Information

Product Name	(3R,4R)-3,4-Dihydroxyoxolan-2-One
CAS No.	17675-99-9
Molecular Formula	C4H6O5
Molecular Weight	134.09 g/mol
Synonyms	(3R,4R)-3,4-Dihydroxy-2-oxotetrahydrofuran; (3R,4R)-Tetrahydro-3,4-dihydroxy-2-furanone; (3R,4R)-Dihydroxybutyrolactone; L-(+)-Dihydroxybutyrolactone; (R,R)-Dihydroxybutyrolactone; (3R,4R)-DHBL; 17675-99-9
EINECS	Contact for details

Quality Control

Our (3R,4R)-3,4-Dihydroxyoxolan-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.