Description

4-Nitrophenyl Glycinate is a specialized chemical ester used as a key reagent and synthetic intermediate in organic synthesis. Its primary value lies in its role as a protecting group for carboxylic acids and as a chromogenic substrate in enzymatic assays, particularly for detecting esterase activity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and biochemical sectors who require high-purity intermediates for complex synthesis and diagnostic development.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, where its ester group serves as a protective moiety.
• Biochemical Research: Acts as a chromogenic substrate for detecting and quantifying esterase and lipase enzyme activity in diagnostic kits and research assays.
• Organic Synthesis: Serves as a versatile building block for constructing glycine derivatives and other amino acid conjugates in medicinal chemistry.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides and plant growth regulators.
• Proteomics & Peptide Chemistry: Utilized in peptide synthesis as a protecting group reagent for carboxylic acid functionalities.
• Dye & Pigment Synthesis: Functions as an intermediate in the production of certain azo dyes and specialty colorants.

Basic Information

Product Name	4-Nitrophenyl Glycinate
CAS No.	17639-39-3
Molecular Formula	C8H8N2O5
Molecular Weight	212.16 g/mol
Synonyms	Glycine, 4-nitrophenyl ester; p-Nitrophenyl glycinate; 4-Nitrophenyl aminoacetate; N-(4-Nitrophenoxycarbonylmethyl)amine; PNPG; 4-Nitrophenyl ester of glycine; (4-Nitrophenoxy)oxoacetamide; Aminoacetic acid 4-nitrophenyl ester
EINECS	Contact for details

Quality Control

Our 4-Nitrophenyl Glycinate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.