Description

(25S)-5β-Spirostane-1β,3β,27-Triol CAS NO 17634-26-3 is a high-purity, steroidal sapogenin derivative characterized by its specific hydroxylation pattern at the 1β, 3β, and 27 positions. This compound serves as a critical advanced pharmaceutical intermediate and a valuable reference standard for analytical and research purposes. It is primarily required by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions engaged in steroid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel steroid-based therapeutics and bioactive molecules.
• Reference Standard: Used in analytical method development, validation, and quality control (QC) testing for related steroid compounds.
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways, enzyme inhibition, and receptor binding assays.
• Academic & Discovery Chemistry: Serves as a starting material or model compound for medicinal chemistry programs and structural-activity relationship (SAR) studies.
• Process Development: Utilized in scaling up synthetic routes and optimizing manufacturing processes for steroidal active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(25S)-5β-Spirostane-1β,3β,27-Triol
CAS No.	17634-26-3
Molecular Formula	C27H44O5
Molecular Weight	448.64 g/mol
Synonyms	1β,3β,27-Trihydroxy-(25S)-5β-spirostan; (25S)-1β,3β,27-Trihydroxy-5β-spirostan; 5β-Spirostane-1β,3β,27-triol, (25S)-; Tigogenin 1β,3β,27-triol derivative; (25S)-Spirostane-1,3,27-triol; 1β,3β,27-Trihydroxytigogenin; 27-Hydroxytigogenin-1,3-diol
EINECS	Contact for details

Quality Control

Our (25S)-5β-Spirostane-1β,3β,27-Triol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for materials intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.