Description

Ethanone, 1-[(1R,2S)-2-Phenylcyclopropyl]-, Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters because its unique cyclopropyl ketone structure, featuring a phenyl substituent, provides a rigid, three-dimensional scaffold that is highly valuable for constructing complex molecules with specific spatial orientations. Pharmaceutical and agrochemical research and development teams need this precise chiral intermediate for applications in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals where stereochemistry is critical to biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), especially for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the specific spatial configuration enhances efficacy and reduces environmental impact.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands and catalysts used in enantioselective transformations.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored optical or electronic properties.
• Academic & Industrial R&D: A valuable tool for chemists in universities and corporate labs exploring new synthetic methodologies and structure-activity relationships (SAR).
• Flavor & Fragrance Chemistry: Potential use as an intermediate for synthesizing complex, naturally-derived aroma compounds with specific stereochemistry.

Basic Information

Product Name	Ethanone, 1-[(1R,2S)-2-Phenylcyclopropyl]-, Rel- (9Ci)
CAS No.	17597-82-9
Molecular Formula	C11H12O
Molecular Weight	160.21 g/mol
Synonyms	rel-(1R,2S)-2-Phenylcyclopropyl methyl ketone; 1-[(1R,2S)-2-Phenylcyclopropyl]ethanone; (1R,2S)-2-Acetyl-1-phenylcyclopropane; (1R,2S)-2-Phenylcyclopropyl methyl ketone; trans-2-Phenylcyclopropyl methyl ketone (relative configuration); Chiral phenylcyclopropyl ketone; Arylcyclopropyl ketone intermediate
EINECS	Contact for details

Quality Control

Our Ethanone, 1-[(1R,2S)-2-Phenylcyclopropyl]-, Rel- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure high chemical and enantiomeric purity suitable for demanding R&D and scale-up processes. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under an inert atmosphere (e.g., nitrogen or argon), please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.