Description

(7R,9As)-1,2,3,8,9,9A-Hexahydro-6-Hydroxy-3',5-Dimethoxy-1-Methylspiro[7H-Benzo[De]Quinoline-7,1'-[2,5]Cyclohexadien]-4'-One is a complex spirocyclic alkaloid derivative of significant interest in advanced organic synthesis. This compound serves as a high-value chemical intermediate for the research and development of novel pharmacologically active molecules. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating new therapeutic agents, particularly within the alkaloid and heterocyclic chemistry domains.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel alkaloid-based drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Organic Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and reaction optimization.
• Academic & Industrial R&D: Employed in research exploring new spirocyclic and polycyclic compound synthesis pathways.
• Biochemical Probe Development: Potential use in developing tools for studying biological pathways and target engagement.

Basic Information

Item	Detail
Product Name	(7R,9As)-1,2,3,8,9,9A-Hexahydro-6-Hydroxy-3',5-Dimethoxy-1-Methylspiro[7H-Benzo[De]Quinoline-7,1'-[2,5]Cyclohexadien]-4'-One
CAS No.	17441-87-1
Molecular Formula	C22H25NO4
Molecular Weight	367.44 g/mol
Synonyms	1,2,3,8,9,9a-Hexahydro-6-hydroxy-3',5-dimethoxy-1-methylspiro[7H-benzo[de]quinoline-7,1'(2'H)-cyclohexa-2,5-dien]-4'-one; Spiro[7H-benzo[de]quinoline-7,1'(2'H)-cyclohexa-2,5-dien]-4'-one, 1,2,3,8,9,9a-hexahydro-6-hydroxy-3',5-dimethoxy-1-methyl-; (7R,9aS)-1,2,3,8,9,9a-Hexahydro-6-hydroxy-3',5-dimethoxy-1-methylspiro[7H-benzo[de]quinoline-7,1'-[2,5]cyclohexadien]-4'-one; Glaucine metabolite; Glaucine derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.