Description

2-O,3-O,4-O,5-O,6-o-Pentaacetyl-D-Glucose 1,2-Ethanediyl Dithioacetal is a key protected carbohydrate derivative, specifically a fully acetylated glucose dithioacetal. This compound is a crucial synthetic intermediate, prized for its role in masking reactive hydroxyl groups and providing a stable platform for stereoselective glycosylation and other complex organic transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex molecules, including nucleoside analogs and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel drug candidates, particularly nucleoside analogs and complex glycoconjugates.
• Glycosylation Chemistry: Used as a glycosyl donor precursor in stereoselective glycosylation reactions to construct oligosaccharides and glycoconjugates.
• Carbohydrate Chemistry Research: A fundamental reagent in academic and industrial research for studying and developing new methodologies in sugar protection, deprotection, and functionalization.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, chiral auxiliaries, and ligands for asymmetric catalysis.
• Agrochemical Development: Acts as an intermediate in the synthesis of advanced, biologically active compounds for crop protection.

Basic Information

Product Name	2-O,3-O,4-O,5-O,6-o-Pentaacetyl-D-Glucose 1,2-Ethanediyl Dithioacetal
CAS No.	17429-98-0
Molecular Formula	C19H28O11S2
Molecular Weight	496.55 g/mol
Synonyms	1,2-Ethanedithiol Acetal of Pentaacetyl-D-Glucose; D-Glucose, 1,2-ethanediyl dithioacetal, pentaacetate; Pentaacetyl-D-glucose ethylene dithioacetal; 1,2-Bis[(2,3,4,5,6-penta-O-acetyl-β-D-glucopyranosyl)thio]ethane (related); Acetylated Glucose Ethylene Dithioacetal; 17429-98-0; D-Glucose pentaacetate ethylene dithioacetal
EINECS	Contact for details

Quality Control

Our 2-O,3-O,4-O,5-O,6-o-Pentaacetyl-D-Glucose 1,2-Ethanediyl Dithioacetal is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications in GMP and research environments where material consistency is paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Specific range available on COA
Specific Rotation	Specific range available on COA
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.