Description

Diethyl 2-[(2-Nitrophenyl)Methylidene]Propanedioate is a specialized organic compound belonging to the class of propanedioate (malonate) esters, characterized by its nitrophenyl functional group. This chemical serves as a versatile and valuable building block (synthon) in advanced organic synthesis, particularly for constructing complex heterocyclic and pharmaceutical intermediates. It is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, reliable intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing quinoline, indole, or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive ester and nitrophenyl groups.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and other specialty organic compounds requiring specific aromatic and ester functionalities.
• Academic & Industrial Research: Employed in methodological development and as a starting material for novel organic reactions, including Knoevenagel condensations and cyclization studies.
• Material Science: Potential monomer or cross-linking agent in the development of advanced polymeric materials with specific optical or electronic properties.

Basic Information

Product Name	Diethyl 2-[(2-Nitrophenyl)Methylidene]Propanedioate
CAS No.	17422-56-9
Molecular Formula	C₁₄H₁₅NO₆
Molecular Weight	293.27 g/mol
Synonyms	Diethyl (2-Nitrobenzylidene)malonate; Propanedioic acid, [(2-nitrophenyl)methylene]-, diethyl ester; 2-Nitrobenzylidenemalonic Acid Diethyl Ester; Diethyl 2-((2-Nitrophenyl)methylene)malonate; (2-Nitrobenzylidene)malonic Acid Diethyl Ester; Ethyl (2-Nitrobenzylidene)malonate; Diethyl (2-Nitrobenzylidene)propanedioate
EINECS	Contact for details

Quality Control

Our Diethyl 2-[(2-Nitrophenyl)Methylidene]Propanedioate is produced and tested under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for synthetic intermediates. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC or GC), identity (IR, NMR), and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.