Description

2-Phenoxy-1,1,1-trifluoroethane is a specialized fluorinated aromatic ether compound, identified by CAS NO 17351-95-0. This chemical is valued for its unique combination of an aromatic ether moiety and a trifluoroethyl group, making it a versatile intermediate and solvent in advanced synthesis. It is primarily sought after by R&D laboratories and industrial manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel compounds and formulations.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic structures for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoroethoxy group can improve biological activity and environmental persistence.
• Specialty Solvent: Acts as a highly volatile and polar aprotic solvent for reactions involving strong acids and organic solvents, useful in polymer chemistry and material science.
• Liquid Crystal & OLED Material Precursor: Serves as an intermediate in the manufacture of fluorinated components for electronic display and lighting technologies.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new fluorination methodologies and creating novel chemical entities.

Basic Information

Product Name	2-Phenoxy-1,1,1-Trifluoroethane
CAS No.	17351-95-0
Molecular Formula	C8H7F3O
Molecular Weight	176.14 g/mol
Synonyms	1,1,1-Trifluoro-2-phenoxyethane; Phenoxytrifluoroethane; α,α,α-Trifluoroethyl phenyl ether; 2,2,2-Trifluoroethyl phenyl ether; (Trifluoroethoxy)benzene; Benzene, (2,2,2-trifluoroethoxy)-; Phenyl trifluoroethyl ether; Trifluoroethyl Phenylether
EINECS	Contact for details

Quality Control

Every batch of 2-Phenoxy-1,1,1-trifluoroethane is produced and tested under a strict quality management system. Our products undergo rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment and is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.25 g/mL
Refractive Index (n20D)	~1.42

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.