Description

(1-Isocyanoethyl)Benzene is a versatile organic building block featuring a reactive isocyanide functional group. This compound is valued for its role as a key precursor in multicomponent reactions and heterocyclic synthesis, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel compounds and fine chemicals.

Application

• Pharmaceutical Intermediates: A critical precursor in the synthesis of heterocyclic compounds and active pharmaceutical ingredients (APIs) via Passerini and Ugi multicomponent reactions.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its reactivity to introduce specific functional groups.
• Ligand and Catalyst Development: Serves as a building block for creating specialized isocyanide-based ligands used in transition metal catalysis.
• Polymer and Material Science: Employed in the synthesis of functional polymers and advanced materials with tailored properties.
• Chemical Biology and Proteomics: Utilized in bioorthogonal chemistry and as a probe for labeling and studying biological systems.
• Academic and Industrial R&D: A fundamental reagent for methodological development in organic synthesis and discovery chemistry.

Basic Information

Product Name	(1-Isocyanoethyl)Benzene
CAS No.	17329-20-3
Molecular Formula	C9H9N
Molecular Weight	131.18 g/mol
Synonyms	1-Isocyanato-1-phenylethane; α-Methylbenzyl isocyanide; (1-Isocyanatoethyl)benzene; Phenethyl isocyanide; Benzyl isocyanide, α-methyl-; Isocyanomethylethylbenzene; 1-Phenylethyl isocyanide
EINECS	Contact for details

Quality Control

Our (1-Isocyanoethyl)Benzene is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers should be kept tightly sealed and opened only under an inert atmosphere when necessary to prevent degradation and moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.