Description

Spiro[2.3]Hexane-1-Carboxylic Acid Ethyl Ester is a specialized spirocyclic organic building block of significant interest in advanced synthetic chemistry. This compound matters for its unique three-dimensional structure, which provides a rigid, sterically defined scaffold for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, ligand design, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, where its spirocyclic core can impart favorable biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal and mechanical properties.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, including ring-opening and functionalization reactions.
• Fine Chemical Production: Employed in the custom synthesis of high-value, complex organic molecules for various industrial applications.

Basic Information

Product Name	Spiro[2.3]Hexane-1-Carboxylic Acid Ethyl Ester
CAS No.	17202-57-2
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	Ethyl Spiro[2.3]hexane-1-carboxylate; Ethyl 1-Spiro[2.3]hexanecarboxylate; 1-Carbethoxy-spiro[2.3]hexane; Spiro[2.3]hexane-1-carboxylic acid ethyl ester; 1-Ethoxycarbonylspiro[2.3]hexane; Spiro(2.3)hexane-1-carboxylic acid, ethyl ester; Ethyl 1-azaspiro[2.3]hexane-1-carboxylate (related structure); Bicyclo[2.1.1]hexane-1-carboxylic acid, ethyl ester (alternative naming)
EINECS	Contact for details

Quality Control

Our Spiro[2.3]Hexane-1-Carboxylic Acid Ethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality systems are designed to support cGMP and ISO standards for reliable use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.