Description

Spiro[2.3]Hexane-1-Carboxylic Acid is a specialized spirocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its unique, rigid spirocyclic framework makes it a valuable precursor for constructing complex molecular architectures with defined three-dimensional geometry. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides and fungicides, leveraging its spirocyclic structure for enhanced biological activity.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Acts as a monomer or precursor for developing polymers and advanced materials with specific steric and electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and exploration of new chemical spaces.

Basic Information

Product Name	Spiro[2.3]Hexane-1-Carboxylic Acid
CAS No.	17202-56-1
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	1-Carboxyspiro[2.3]hexane; Spiro[2.3]hexane-1-carboxylic acid; 1-Spiro[2.3]hexanecarboxylic acid; Bicyclo[2.1.1]hexane-1-carboxylic acid (related structural name); 1-Carboxybicyclo[2.1.1]hexane; Spirohexane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our Spiro[2.3]Hexane-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopic methods, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, it is recommended to keep the material under an inert atmosphere at temperatures between 2°C and 8°C to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.