Description

Spiro[2.4]Heptan-1-Amine Hydrochloride is a specialized organic salt featuring a unique spirocyclic amine structure, making it a valuable building block in advanced chemical synthesis. Its primary commercial value lies in its role as a key chiral intermediate for the research and development of novel pharmaceutical compounds and fine chemicals. This high-purity intermediate is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce complex, three-dimensional frameworks into their target molecules.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, where its spirocyclic structure can contribute to unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring complex amine backbones.
• Academic and Industrial R&D: A valuable reagent for methodological research in organic chemistry, enabling studies on ring strain and reactivity.
• Material Science: Potential monomer or additive for developing polymers with specific thermal or mechanical properties.

Basic Information

Product Name	Spiro[2.4]Heptan-1-Amine Hydrochloride
CAS No.	17202-53-8
Molecular Formula	C7H12ClN
Molecular Weight	145.63 g/mol
Synonyms	1-Aminospiro[2.4]heptane Hydrochloride; Spiro[2.4]heptan-1-amine, hydrochloride; 1-Azaspiro[2.4]heptane, hydrochloride; 1-Aminospiro[2.4]heptane HCl; Spiroheptane-1-amine hydrochloride; 17202-53-8; 1-Aminobicyclo[3.1.0]hexane hydrochloride
EINECS	Contact for details

Quality Control

Our Spiro[2.4]Heptan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.