Description

5-[Bis(2-Chloroethyl)Amino]-m-Toluic Acid is a specialized nitrogen mustard derivative of toluic acid, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of targeted pharmaceutical agents and sophisticated chemical probes. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential alkylating agents and prodrugs.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of novel chemotherapeutic agents and targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new nitrogen mustard-based compounds with modified pharmacological profiles.
• Bioconjugation: Serves as a reactive handle for attaching payloads to antibodies, peptides, or other targeting molecules in the development of antibody-drug conjugates (ADCs).
• Chemical Biology: Employed in the synthesis of molecular probes to study DNA alkylation and cellular repair mechanisms.
• Organic Synthesis Building Block: Utilized in multi-step syntheses to introduce the bis(2-chloroethyl)amino functional group into complex molecular architectures.

Basic Information

Product Name	5-[Bis(2-Chloroethyl)Amino]-m-Toluic Acid
CAS No.	17191-65-0
Molecular Formula	C13H17Cl2NO2
Molecular Weight	290.19 g/mol
Synonyms	5-[Bis(2-chloroethyl)amino]-3-methylbenzoic acid; m-Toluic acid, 5-[bis(2-chloroethyl)amino]-; NSC 82196; 3-Methyl-5-[bis(2-chloroethyl)amino]benzoic acid; 5-(Bis(2-chloroethyl)amino)-3-methylbenzoic acid; Benzoic acid, 3-methyl-5-[bis(2-chloroethyl)amino]-
EINECS	Contact for details

Quality Control

Our 5-[Bis(2-Chloroethyl)Amino]-m-Toluic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.