Description

Methyl 4-Chloro-4-Oxobut-2-Enoate is a versatile and highly reactive α,β-unsaturated ester derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an acid chloride and an acrylate moiety, makes it an indispensable precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as the synthesis of heterocycles, active pharmaceutical ingredients (APIs), and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various heterocyclic compounds and complex drug molecules, particularly those requiring a reactive handle for further functionalization.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its reactive sites allow for the introduction of specific bioactive groups.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored properties, such as coatings, adhesives, and functional materials.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies, including cycloaddition reactions and nucleophilic substitutions.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other performance chemicals that require precise molecular engineering.

Basic Information

Product Name	Methyl 4-Chloro-4-Oxobut-2-Enoate
CAS No.	17081-97-9
Molecular Formula	C5H5ClO3
Molecular Weight	148.54 g/mol
Synonyms	4-Chloro-4-oxobut-2-enoic acid methyl ester; Methyl (E)-4-chloro-4-oxobut-2-enoate; Methyl 4-chloroacetoacetate (unsaturated form); 2-Butenoic acid, 4-chloro-4-oxo-, methyl ester; Methyl 4-chloro-3-buten-2-one-4-oate; Acetylacrylic acid methyl ester chloride; Methyl β-chloroacetoacetate (unsaturated)
EINECS	Contact for details

Quality Control

Our Methyl 4-Chloro-4-Oxobut-2-Enoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its reactivity as a strong acid/organic solvent derivative, keep away from heat, open flames, and incompatible materials such as bases, oxidizing agents, and amines. Keep the container tightly sealed when not in use to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.