Description

5-Ethyl-5-(1-Methyl-2-Butenyl)Barbituric Acid is a specialized barbiturate derivative, a class of compounds historically significant in medicinal chemistry. Its precise molecular structure makes it a valuable intermediate or reference standard for pharmaceutical research and development. This compound is primarily required by research institutions, analytical laboratories, and fine chemical manufacturers engaged in developing or testing central nervous system (CNS) active agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel barbiturate-based compounds for pharmacological evaluation.
• Analytical Reference Standard: Used in high-performance liquid chromatography (HPLC), gas chromatography (GC), and mass spectrometry (MS) for method development, calibration, and quality control of related substances.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of barbiturates and their interaction with biological targets like GABA receptors.
• Chemical Synthesis: Acts as a precursor for the preparation of more complex heterocyclic molecules in academic and industrial research settings.
• Forensic Science: May be utilized as a controlled substance analog or metabolite standard in forensic toxicology analyses.

Basic Information

Product Name	5-Ethyl-5-(1-Methyl-2-Butenyl)Barbituric Acid
CAS No.	17013-35-3
Molecular Formula	C12H16N2O3
Molecular Weight	236.27 g/mol
Synonyms	5-Ethyl-5-(1-methylbut-2-en-1-yl)-1,3-diazinane-2,4,6-trione; 5-Ethyl-5-(1-methyl-2-butenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Ethyl-5-(1-methyl-2-butenyl)barbituric acid; 5-(1-Methyl-2-butenyl)-5-ethylbarbituric acid; 5-Allyl-5-ethyl-1-methylbarbituric acid (related structure); NSC 32918; Barbituric acid, 5-ethyl-5-(1-methyl-2-butenyl)-
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(1-Methyl-2-Butenyl)Barbituric Acid is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided, documenting the identity, purity, and specifications to ensure it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.