Description

5-(Trimethylsilyl)-2-Pentanone is a specialized organosilicon compound featuring a ketone functional group protected by a trimethylsilyl moiety. This unique structure makes it a valuable silylating agent and protected synthetic intermediate in advanced organic synthesis. It is primarily used by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules where selective protection and deprotection strategies are critical.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing or protecting ketone functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its silicon group aids in stability and bioavailability.
• Organometallic Chemistry: Acts as a precursor or ligand modifier in catalytic systems and metal-organic frameworks (MOFs).
• Polymer & Material Science: Employed in the synthesis of silicon-containing polymers, resins, and specialty coatings to modify surface properties.
• Flavor & Fragrance Industry: Utilized as an intermediate for creating complex musk and other specialty aroma chemicals.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis and new reaction discovery.

Basic Information

Product Name	5-(Trimethylsilyl)-2-Pentanone
CAS No.	17012-93-0
Molecular Formula	C8H18OSi
Molecular Weight	158.31 g/mol
Synonyms	5-(Trimethylsilyl)pentan-2-one; 2-Pentanone, 5-(trimethylsilyl)-; 5-Trimethylsilyl-2-pentanone; 1-Trimethylsilyl-4-butanone; 4-(Trimethylsilyl)butyl methyl ketone; TMS-protected 2-pentanone; (4-Oxopentyl)trimethylsilane
EINECS	Contact for details

Quality Control

Our production of 5-(Trimethylsilyl)-2-Pentanone adheres to stringent quality protocols. Each batch undergoes comprehensive analysis including GC, HPLC, and NMR to verify identity, purity, and the absence of critical impurities. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C to minimize volatility and oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.