Description

n-(Trifluoroacetyl)-L-Valine 1-Methylpropyl Ester is a specialized chiral building block and derivatization reagent. This compound is valued for its role in the synthesis and analysis of complex organic molecules, particularly peptides and amino acid derivatives. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for process development and analytical method development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Analytical Derivatization Agent: Used to enhance the detectability and separation of amino acids and chiral amines in chromatographic analysis (e.g., GC, HPLC).
• Agrochemical Research: Serves as a building block for developing novel chiral pesticides and herbicides.
• Peptide Chemistry: Employed in peptide coupling reactions and for the temporary protection of amino groups during solid-phase peptide synthesis (SPPS).
• Chemical Biology Probes: Used in the design and synthesis of labeled compounds for studying biological mechanisms.
• Material Science: A precursor for creating specialized polymers and coatings with unique fluorinated properties.

Basic Information

Product Name	n-(Trifluoroacetyl)-L-Valine 1-Methylpropyl Ester
CAS No.	16974-92-8
Molecular Formula	C11H18F3NO3
Molecular Weight	269.26 g/mol
Synonyms	L-Valine, N-[(trifluoroacetyl)-, 1-methylpropyl ester; N-(Trifluoroacetyl)-L-valine sec-butyl ester; N-TFA-L-valine sec-butyl ester; (S)-2-((1-Methylpropoxy)carbonyl)-3-methylbutanoic acid 2,2,2-trifluoroacetamide; sec-Butyl N-(trifluoroacetyl)-L-valinate; Valine, N-trifluoroacetyl-, sec-butyl ester, L-
EINECS	Contact for details

Quality Control

Our n-(Trifluoroacetyl)-L-Valine 1-Methylpropyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container must be kept tightly sealed due to sensitivity to moisture and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.