Description

4-Nitrobenzyl Bromoacetate is a specialized organic synthesis intermediate featuring both a reactive bromoacetate ester group and a nitro-substituted benzyl moiety. This bifunctional structure makes it a valuable building block for the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in fine chemical synthesis, where it serves as a key precursor for introducing functionalized acetic acid derivatives into target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a functionalized acetic acid side chain.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Peptide Mimetics & Linker Chemistry: The reactive bromoacetate group is useful for alkylation reactions in creating peptide analogs or constructing chemical linkers for bioconjugation.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Employed in the synthesis of activity-based probes for studying enzyme function and mechanism.
• Academic & Industrial R&D: A versatile reagent for methodological development and exploratory organic synthesis in laboratory settings.

Basic Information

Product Name	4-Nitrobenzyl Bromoacetate
CAS No.	16869-24-2
Molecular Formula	C9H8BrNO4
Molecular Weight	274.07 g/mol
Synonyms	Bromoacetic Acid 4-Nitrobenzyl Ester; (4-Nitrophenyl)methyl 2-bromoacetate; p-Nitrobenzyl Bromoacetate; 4-Nitrobenzyl 2-bromoacetate; 2-Bromoacetic Acid 4-Nitrobenzyl Ester; Bromoacetyl 4-nitrobenzyl ester; NSC 401119; 4-Nitrobenzyl α-bromoacetate
EINECS	Contact for details

Quality Control

Our 4-Nitrobenzyl Bromoacetate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.