Description

8-Phenethyl-1,4-dioxa-8-azaspiro[4.5]decane is a specialized heterocyclic building block featuring a spirocyclic structure that combines dioxolane and piperidine motifs. This compound matters as a versatile and high-value synthetic intermediate, enabling the construction of complex molecular architectures for advanced research and development. It is primarily needed by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry, particularly in the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting the central nervous system.
• Medicinal Chemistry Research: Used for scaffold hopping and structure-activity relationship (SAR) studies due to its constrained, three-dimensional spirocyclic core.
• Agrochemical Synthesis: Intermediate in the development of new pesticides and herbicides requiring specific heterocyclic frameworks.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological targets and pathways.
• Academic and Industrial R&D: Fundamental research chemical for exploring new synthetic methodologies and novel compound libraries.

Basic Information

Product Name	8-Phenethyl-1,4-dioxa-8-azaspiro[4.5]decane
CAS No.	16771-89-4
Molecular Formula	C15H21NO2
Molecular Weight	247.33 g/mol
Synonyms	8-Phenethyl-1,4-dioxa-8-azaspiro[4.5]decane; 1,4-Dioxa-8-azaspiro[4.5]decane, 8-(2-phenylethyl)-; 8-(2-Phenylethyl)-1,4-dioxa-8-azaspiro[4.5]decane; 8-Phenethyl-1,4-dioxa-8-azaspiro[4,5]decane; Phenethyl Dioxa Aza Spirodecane; Spirocyclic Dioxolane-Piperidine Derivative
EINECS	Contact for details

Quality Control

Our 8-Phenethyl-1,4-dioxa-8-azaspiro[4.5]decane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), identity (IR, NMR), and impurity profiles. Our quality commitment supports cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.