Description

2-[1,3-Bis[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methyl]-1,3-Diazinan-2-Yl]-4-Nitro-Phenol is a complex, high-value nitrogen mustard derivative with a phenolic nitro group, designed for advanced chemical synthesis and research. This compound matters for its role as a sophisticated chemical building block in the development of specialized pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on oncology research and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex nitrogen mustard-based chemotherapeutic agents and targeted cancer therapies.
• Biochemical Research: Used in academic and industrial research to study alkylating agent mechanisms, DNA cross-linking, and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex molecular architectures in medicinal chemistry and drug discovery programs.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Oncology Drug Development: Integral to R&D pipelines focused on creating new alkylating antineoplastic agents with modified potency and selectivity.

Basic Information

Product Name	2-[1,3-Bis[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methyl]-1,3-Diazinan-2-Yl]-4-Nitro-Phenol
CAS No.	16757-47-4
Molecular Formula	C32H40Cl4N6O3
Molecular Weight	698.51 g/mol
Synonyms	Phenol, 2-[1,3-bis[[4-[bis(2-chloroethyl)amino]phenyl]methyl]-1,3-diazinan-2-yl]-4-nitro-; 4-Nitro-2-[1,3-bis({4-[bis(2-chloroethyl)amino]phenyl}methyl)-1,3-diazinan-2-yl]phenol; 2-(1,3-Bis({4-[bis(2-chloroethyl)amino]phenyl}methyl)-1,3-diazinan-2-yl)-4-nitrophenol; Nitrogen Mustard Phenol Derivative; Bis(chloroethyl)amino phenylmethyl diazinanyl nitrophenol
EINECS	Contact for details

Quality Control

Every batch of 2-[1,3-Bis[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methyl]-1,3-Diazinan-2-Yl]-4-Nitro-Phenol is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with stringent purity standards for research and pharmaceutical applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.