Description

Allyl Orthoformate is a specialized organic ester compound with the CAS registry number 16754-50-0. This versatile chemical intermediate is valued for its unique reactivity, particularly as a protective group for carbonyls and a precursor in complex organic synthesis. It is essential for research chemists and process developers in the pharmaceutical, agrochemical, and fine chemical industries seeking to build complex molecular architectures efficiently.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing allyl-protected functional groups.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where its orthoester functionality enables specific ring closures and modifications.
• Fine Chemical Production: Serves as a crucial reagent for manufacturing flavors, fragrances, and specialty polymers requiring controlled release or specific degradation profiles.
• Organic Synthesis Reagent: Acts as a versatile protecting group for aldehydes and ketones in multi-step synthetic routes, preventing unwanted side reactions.
• Cross-coupling Reactions: Employed as a substrate in palladium-catalyzed reactions, such as the Tsuji-Trost reaction, for forming carbon-carbon bonds.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of novel polymeric materials with tailored properties.

Basic Information

Product Name	Allyl Orthoformate
CAS No.	16754-50-0
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	Triallyl Orthoformate; Orthoformic Acid Triallyl Ester; Allyl Orthoformate; 2-Propen-1-yl Orthoformate; Tri-2-propenyl Orthoformate; Formic Acid, Tri-2-propenyl Ester; NSC 5186; Tris(allyloxy)methane
EINECS	240-826-7

Quality Control

Our Allyl Orthoformate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your R&D and production needs with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. The container should be kept tightly sealed when not in use to minimize moisture absorption and prevent volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.420 - 1.430
Density (20°C)	0.95 - 0.99 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.