Description

Orthoformic Acid Triisobutyl Ester is a specialized organic ester of orthoformic acid, valued for its role as a versatile reagent and protecting group in advanced chemical synthesis. Its structure makes it particularly useful for introducing the triisobutyl orthoformate moiety into target molecules under controlled conditions. This compound is essential for research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and fine chemical sectors, where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate: Acts as a key building block and protecting group in the synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of pesticides, herbicides, and other crop protection agents.
• Fine Chemical Manufacturing: Serves as a reagent for the preparation of complex organic molecules, flavors, and fragrances.
• Laboratory Research: Employed in academic and industrial R&D for method development and exploratory synthesis.
• Polymer Chemistry: Can be utilized as a modifier or cross-linking agent in specialty polymer formulations.
• Chemical Derivatization: Useful for protecting aldehyde groups or as a formylating agent in multi-step synthetic sequences.

Basic Information

Product Name	Orthoformic Acid Triisobutyl Ester
CAS No.	16754-49-7
Molecular Formula	C13H28O3
Molecular Weight	232.36 g/mol
Synonyms	Triisobutyl Orthoformate; Formic Acid, Triisobutyl Ester; Triisobutyl Methanetriyl Trioxydiisobutane; Orthoformic Acid Triisobutyl Ester; Isobutyl Orthoformate; HC(OCH2CH(CH3)2)3; Tris(2-methylpropyl) Orthoformate
EINECS	240-826-8

Quality Control

Our Orthoformic Acid Triisobutyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from strong acids and organic solvents. Recommended storage temperature is 2-25°C. Keep container tightly sealed when not in use to minimize moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.410 - 1.420
Density (20°C)	0.88 - 0.92 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.