Description

3-o-Acetyl-1,2:5,6-Di-o-Isopropylidene-α-D-Glucofuranose CAS NO 16713-80-7 is a key protected carbohydrate intermediate, specifically an acetylated derivative of diacetone glucose. This compound is valued for its role as a versatile chiral building block in organic synthesis, enabling the stereoselective construction of complex molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of nucleoside analogs, glycosidase inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Chiral Building Block: Used in asymmetric synthesis to introduce the D-glucose scaffold into complex target molecules with high stereochemical fidelity.
• Glycochemistry Research: Serves as a protected glycosyl donor or acceptor for the study and synthesis of complex carbohydrates and glycoconjugates.
• Agrochemical Synthesis: Employed in the development of chiral active ingredients for herbicides and fungicides.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances requiring specific sugar-derived chirality.
• Academic & Process R&D: A standard reagent in laboratory-scale research for method development and exploring new synthetic pathways.

Basic Information

Product Name	3-o-Acetyl-1,2:5,6-Di-o-Isopropylidene-α-D-Glucofuranose
CAS No.	16713-80-7
Molecular Formula	C14H22O7
Molecular Weight	302.32 g/mol
Synonyms	1,2:5,6-Di-O-Isopropylidene-α-D-glucofuranose 3-Acetate; 3-O-Acetyl-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose; 3-Acetyl Diacetone Glucose; Diacetone Glucose 3-Acetate; 1,2:5,6-Di-O-isopropylidene-α-D-allofuranose 3-acetate; α-D-Glucofuranose, 1,2:5,6-di-O-(1-methylethylidene)-, 3-acetate; 3-O-Acetyl Diacetone D-Glucose
EINECS	240-774-9

Quality Control

Our 3-o-Acetyl-1,2:5,6-Di-o-Isopropylidene-α-D-Glucofuranose is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and quality assurance for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Specific Rotation [α]20/D	-19° to -23° (c=1 in CHCl3)
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.