Description

3,5-Bis(Trifluoromethyl)Phenyl Isocyanate is a highly reactive aromatic isocyanate derivative, distinguished by the presence of two electron-withdrawing trifluoromethyl groups on the phenyl ring. This structural feature makes it a critical building block for synthesizing advanced materials with enhanced chemical resistance, thermal stability, and unique surface properties. It is primarily sought after by R&D chemists and process engineers in the agrochemical, pharmaceutical, and specialty polymer industries for creating high-performance intermediates, active ingredients, and functional coatings.

Application

• Agrochemical Intermediates: Key precursor for synthesizing advanced herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Pharmaceutical Synthesis: Used in the construction of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) that require fluorinated aromatic moieties for improved metabolic stability and bioavailability.
• Specialty Polymers & Resins: Serves as a monomer for producing high-performance polyurethanes, polyureas, and other polymers with superior chemical, thermal, and weathering resistance for coatings, adhesives, and elastomers.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: A valuable reagent for developing novel fluorinated materials, including liquid crystals, organic semiconductors, and advanced composites with low surface energy.
• Crosslinking Agent: Functions as an efficient crosslinker for hydroxyl- or amine-containing polymers, enhancing the mechanical strength and durability of the final network.

Basic Information

Product Name	3,5-Bis(Trifluoromethyl)Phenyl Isocyanate
CAS No.	16588-74-2
Molecular Formula	C9H3F6NO
Molecular Weight	255.12 g/mol
Synonyms	3,5-Bis(trifluoromethyl)phenyl isocyanate; 1-Isocyanato-3,5-bis(trifluoromethyl)benzene; 3,5-Bis(trifluoromethyl)benzenisocyanate; α,α,α,α',α',α'-Hexafluoro-3,5-xylylene isocyanate; 3,5-Di(trifluoromethyl)phenyl isocyanate; Isocyanic acid, 3,5-bis(trifluoromethyl)phenyl ester
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Trifluoromethyl)Phenyl Isocyanate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and IR for structural confirmation, to ensure it meets exacting specifications for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to minimize volatility and degradation. Due to its highly volatile and moisture-sensitive nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, amines, alcohols, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.55 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.