Description

2-Nitro-4-(Trifluoromethyl)Phenyl Isocyanate is a versatile and highly reactive aromatic isocyanate building block. This compound is critical for the synthesis of advanced chemical intermediates, particularly in the development of specialized polymers and active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process engineers in the agrochemical, pharmaceutical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, pesticides, and plant growth regulators, leveraging the biological activity of the trifluoromethyl and nitro substituents.
• Pharmaceutical Synthesis: Used to create urea and carbamate derivatives that serve as core structures or pharmacophores in drug discovery programs for various therapeutic areas.
• Specialty Polymer Production: Serves as a monomer or cross-linking agent in the manufacture of high-performance polyurethanes, polyureas, and coatings with enhanced chemical resistance and durability.
• Chemical Research & Development: An essential reagent for constructing diverse heterocyclic compounds and other complex organic molecules in academic and industrial research laboratories.
• Dye and Pigment Manufacturing: Employed in the synthesis of advanced colorants and functional dyes due to the electron-withdrawing properties of its substituents.
• Material Science: Used to modify surface properties and create advanced functional materials with specific adhesion or release characteristics.

Basic Information

Product Name	2-Nitro-4-(Trifluoromethyl)Phenyl Isocyanate
CAS No.	16588-70-8
Molecular Formula	C8H3F3N2O3
Molecular Weight	232.12 g/mol
Synonyms	4-(Trifluoromethyl)-2-nitrophenyl isocyanate; 2-Nitro-α,α,α-trifluoro-p-tolyl isocyanate; 1-Isocyanato-2-nitro-4-(trifluoromethyl)benzene; 2-Nitro-4-trifluoromethylphenyl isocyanate; NSC 403058; 4-Trifluoromethyl-2-nitrophenyl isocyanate; p-(Trifluoromethyl)-o-nitrophenyl isocyanate
EINECS	Contact for details

Quality Control

Every batch of 2-Nitro-4-(Trifluoromethyl)Phenyl Isocyanate undergoes rigorous analytical testing to ensure it meets stringent purity and consistency standards required for sensitive synthetic applications. Our quality assurance protocols are designed to support cGMP and ISO 9001 compliant manufacturing processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, this material must be stored under a dry, inert atmosphere (e.g., nitrogen or argon) in a cool, well-ventilated area. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture ingress.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline solid or liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.