Description

4-Chloro-2-(Trifluoromethyl)Phenyl Isocyanate is a versatile and highly reactive aromatic isocyanate building block, essential for synthesizing advanced chemical intermediates. Its core value lies in introducing the phenyl isocyanate functional group, which readily reacts with amines, alcohols, and other nucleophiles to form ureas and carbamates. This compound is particularly valuable for researchers and manufacturers in the agrochemical and pharmaceutical industries, where it serves as a key precursor for active ingredients and specialty polymers.

Application

• Agrochemical Synthesis: A critical intermediate in the production of modern herbicides, fungicides, and insecticides, where its unique halogenated trifluoromethylphenyl structure contributes to biological activity and environmental stability.
• Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing urea-based pharmacophores in drug discovery programs.
• Polymer & Resin Modification: Serves as a cross-linking agent or chain extender in the synthesis of polyurethanes, polyureas, and other specialty polymers, enhancing material properties like durability and chemical resistance.
• Chemical Research & Development: A valuable reagent in organic synthesis for constructing complex molecules, particularly in academic and industrial R&D settings focused on novel heterocyclic compounds.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments, where the isocyanate group facilitates covalent bonding to substrates or other chromophores.

Basic Information

Item	Detail
Product Name	4-Chloro-2-(Trifluoromethyl)Phenyl Isocyanate
CAS No.	16588-69-5
Molecular Formula	C8H3ClF3NO
Molecular Weight	221.56 g/mol
Synonyms	1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene; 4-Chloro-α,α,α-trifluoro-o-tolyl isocyanate; 2-Trifluoromethyl-4-chlorophenyl isocyanate; Isocyanic acid, 4-chloro-2-(trifluoromethyl)phenyl ester; 4-Chloro-2-trifluoromethylphenyl isocyanate; NSC 405124
EINECS	Contact for details

Quality Control

Every batch of our 4-Chloro-2-(Trifluoromethyl)Phenyl Isocyanate is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards, and comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and product integrity for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation and moisture uptake. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.