Description

Methyl 5-Bromo-1H-Pyrrole-3-Carboxylate is a high-purity brominated pyrrole derivative, a crucial heterocyclic building block for advanced organic synthesis. Its value lies in its functionalized structure, which serves as a versatile intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates targeting various therapeutic areas, including central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the pyrrole core's bioactivity.
• Material Science Precursor: Serves as a building block for functionalized polymers and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and other metal-catalyzed transformations to introduce complex pyrrole motifs.
• Academic & Institutional R&D: A valuable reagent for methodological studies and the discovery of new heterocyclic chemistry in university and government laboratories.

Basic Information

Product Name	Methyl 5-Bromo-1H-Pyrrole-3-Carboxylate
CAS No.	16420-39-6
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	5-Bromo-1H-pyrrole-3-carboxylic acid methyl ester; Methyl 5-bromo-3-pyrrolecarboxylate; 5-Bromo-3-(methoxycarbonyl)-1H-pyrrole; 1H-Pyrrole-3-carboxylic acid, 5-bromo-, methyl ester; 5-Bromopyrrole-3-carboxylic acid methyl ester; Methyl 5-bromo-1H-pyrrole-3-carboxylate; 3-Carbomethoxy-5-bromopyrrole
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-1H-Pyrrole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.