Description

1-Adamantaneacetonitrile is a versatile and highly functionalized organic building block featuring the rigid, lipophilic adamantane cage. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science. Its unique structure makes it essential for chemists and researchers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty polymers. Global industries rely on this high-purity intermediate for its consistent quality and reliable performance in demanding synthetic applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, including antiviral agents, neurological therapeutics, and enzyme inhibitors.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection products, leveraging the stability of the adamantane moiety.
• Material Science Research: Serves as a building block for creating novel polymers, dendrimers, and liquid crystals with enhanced thermal and chemical stability.
• Organic Synthesis & Catalysis: Employed as a versatile nitrile-containing synthon in cycloaddition reactions, cross-coupling, and other catalytic transformations.
• Chemical Biology Probes: Utilized in the development of labeled compounds and molecular probes for studying biological systems and mechanisms.
• High-Performance Lubricant Additives: Acts as a precursor for synthesizing advanced additives that improve the performance of industrial lubricants.

Basic Information

Product Name	1-Adamantaneacetonitrile
CAS No.	16269-13-9
Molecular Formula	C₁₂H₁₇N
Molecular Weight	175.27 g/mol
Synonyms	Adamant-1-ylacetonitrile; 1-Adamantylacetonitrile; (Adamantan-1-yl)acetonitrile; 2-(1-Adamantyl)acetonitrile; 1-Cyanomethyladamantane; Tricyclo[3.3.1.1³,⁷]decane-1-acetonitrile; Adamantane-1-acetonitrile
EINECS	Contact for details

Quality Control

Our 1-Adamantaneacetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR). A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.