Description

3-Amino-1,3-Diaza-Spiro[4.5]Decane-2,4-Dione is a high-purity, specialized spirocyclic hydantoin derivative, serving as a critical building block in advanced organic synthesis. Its unique fused-ring structure provides a rigid, three-dimensional scaffold that is highly valuable for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of spirocyclic drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand & Catalyst Development: Serves as a sophisticated ligand or precursor for asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics & Bioisosteres: Its hydantoin core is utilized to create conformationally restricted peptide analogs and bioisosteric replacements in medicinal chemistry.
• High-Performance Material Precursor: A potential monomer or cross-linker for synthesizing specialty polymers with enhanced thermal or mechanical properties.
• Chemical Biology Probe: Employed in the design of molecular probes to study enzyme function and protein-protein interactions.

Basic Information

Product Name	3-Amino-1,3-Diaza-Spiro[4.5]Decane-2,4-Dione
CAS No.	16252-63-4
Molecular Formula	C8H13N3O2
Molecular Weight	183.21 g/mol
Synonyms	3-Amino-1,3-diazaspiro[4.5]decane-2,4-dione; 3-Aminospiro[imidazolidine-4,1'-cyclohexane]-2,5-dione; 3-Amino-1,3-diazaspiro[4.5]decan-2,4-dione; 3-Amino-1,3-diaza-spiro[4.5]decane-2,4-dione; 3-Amino-1,3-diazaspiro[4.5]decan-2,4-dione; 3-Amino-1,3-diazaspiro[4.5]decane-2,4-dione; 3-Amino-1,3-diazaspiro[4.5]decan-2,4-dione; 3-Amino-1,3-diazaspiro[4.5]decane-2,4-dione
EINECS	Contact for details

Quality Control

Our 3-Amino-1,3-Diaza-Spiro[4.5]Decane-2,4-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.