Description

tert-Butyl 2-(4-Hydroxyphenyl)Acetate is a high-purity organic intermediate featuring a phenolic hydroxyl group protected by a tert-butyl ester. This compound matters for its role as a versatile and stable building block in advanced organic synthesis, enabling the creation of complex molecules with precise functional group control. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of complex drug molecules, particularly those requiring a phenolic moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing advanced organic electronic materials and display components.
• Polymer Modification: Acts as a functional monomer or chain transfer agent for creating specialty polymers with tailored properties.
• Peptide & Protein Research: Employed in the synthesis of non-natural amino acids or as a protecting group strategy in peptide chemistry.
• Flavor & Fragrance Ingredient Synthesis: Used as an intermediate for producing specific aromatic compounds.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory chemistry in university and CRO laboratories.
• Dye & Pigment Manufacturing: Functions as an intermediate in the synthesis of certain high-performance colorants.

Basic Information

Product Name	tert-Butyl 2-(4-Hydroxyphenyl)Acetate
CAS No.	16010-88-1
Molecular Formula	C₁₂H₁₆O₃
Molecular Weight	208.25 g/mol
Synonyms	4-Hydroxyphenylacetic Acid tert-Butyl Ester; 2-(4-Hydroxyphenyl)acetic Acid 1,1-Dimethylethyl Ester; tert-Butyl (4-Hydroxyphenyl)acetate; p-Hydroxyphenylacetic Acid tert-Butyl Ester; 4-(tert-Butoxycarbonylmethyl)phenol; 16010-88-1; tert-Butyl 4-hydroxyphenylacetate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of tert-Butyl 2-(4-Hydroxyphenyl)Acetate is manufactured under a strict quality management system and analyzed using advanced techniques like HPLC, GC, and NMR to confirm identity, purity, and consistency. Certificates of Analysis (COA) are available upon request and provide full traceability and batch-specific data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.