Description

Benzeneacetic Acid, 3-Methoxy-4-[(Trimethylsilyl)Oxy]-, Methyl Ester is a specialized organosilicon-protected intermediate of significant value in synthetic organic chemistry. This compound matters for its role as a key building block in the synthesis of complex molecules, offering a protected phenolic group that can be selectively deprotected under mild conditions. Pharmaceutical, agrochemical, and advanced material research and development teams need it for constructing active pharmaceutical ingredients (APIs), fine chemicals, and novel polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly those containing catechol or guaiacol motifs.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and plant growth regulators where the protected phenolic functionality is required.
• Fine Chemical Production: Serves as a versatile building block for creating specialty chemicals, flavors, fragrances, and dyes.
• Academic & Industrial Research: Employed in research laboratories for method development, catalysis studies, and the exploration of new synthetic pathways.
• Material Science: Potential use in the synthesis of monomers for advanced polymers, resins, and silicon-containing hybrid materials.
• Protecting Group Strategy: The trimethylsilyl (TMS) group provides a stable, yet cleavable, protection for the phenol, enabling selective reactions elsewhere on the molecule.

Basic Information

Product Name	Benzeneacetic Acid, 3-Methoxy-4-[(Trimethylsilyl)Oxy]-, Methyl Ester
CAS No.	15964-84-8
Molecular Formula	C13H20O4Si
Molecular Weight	268.38 g/mol
Synonyms	Methyl 2-(3-Methoxy-4-((trimethylsilyl)oxy)phenyl)acetate; Methyl (3-Methoxy-4-trimethylsilyloxyphenyl)acetate; 2-(3-Methoxy-4-(trimethylsilyloxy)phenyl)acetic Acid Methyl Ester; Methyl 3-Methoxy-4-(trimethylsiloxy)benzeneacetate; 4-(Trimethylsiloxy)-3-methoxyphenylacetic Acid Methyl Ester; TMS-Protected Homovanillic Acid Methyl Ester; Methyl 4-(Trimethylsilyloxy)-3-methoxyphenylacetate
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, 3-Methoxy-4-[(Trimethylsilyl)Oxy]-, Methyl Ester is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can compromise product integrity. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.