Description

(S)-α-Aminobenzeneacetic Acid Ethyl Ester is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound is valued for its role in constructing complex molecules with defined stereochemistry, which is critical for biological activity. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the production of active pharmaceutical ingredients (APIs), chiral catalysts, and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of enantiomerically pure drugs, particularly in β-lactam antibiotics and other therapeutic agents.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• Agrochemical Research: Employed in the development of chiral pesticides and herbicides where specific stereoisomers exhibit enhanced activity.
• Peptidomimetics & Biochemistry: Serves as a protected amino acid derivative for constructing peptide analogs and other bioactive compounds.
• Catalyst & Ligand Preparation: Utilized in the synthesis of novel chiral ligands for transition metal catalysis.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic and medicinal chemistry laboratories.

Basic Information

Product Name	(S)-α-Aminobenzeneacetic Acid Ethyl Ester
CAS No.	15962-49-9
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(S)-Ethyl 2-amino-2-phenylacetate; (S)-2-Phenylglycine ethyl ester; L-Phenylglycine ethyl ester; (S)-α-Aminophenylacetic acid ethyl ester; Ethyl (S)-2-amino-2-phenylacetate; Ethyl (S)-phenylglycinate; (S)-Aminophenylacetic acid ethyl ester; (S)-2-Amino-2-phenylethanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our (S)-α-Aminobenzeneacetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.